The MR SCIENCE lab has published a novel algorithm, referred to as Dephasing Optimization Through Coherence Order Pathway Selection (DOTCOPS), which designs crusher schemes for any magnetic resonance spectroscopy experiment, and can be used for any metabolite of interest. DOTCOPS uses a numerical optimization to provide maximum crushing to all unwanted coherence pathways, thereby eliminating the effects of spurious echoes which can contaminate the spectrum or cause voxel mislocalization. Postdoctoral fellow Karl Landheer has first authored the publication, which is published in Magnetic Resonance in Medicine:
Karl Landheer, Christoph Juchem. (2018). Dephasing optimization through coherence order pathway selection (DOTCOPS) for improved crusher schemes in MR spectroscopy. Magnetic Resonance in Medicine. [Epub ahead of print]. https://doi.org/10.1002/mrm.27587