The MR SCIENCE lab has published a novel algorithm, referred to as Dephasing Optimization Through Coherence Order Pathway Selection (DOTCOPS), which designs crusher schemes for any magnetic resonance spectroscopy experiment, and can be used for any metabolite of interest. DOTCOPS uses a numerical optimization to provide maximum crushing to all unwanted coherence pathways, thereby eliminating the effects of spurious echoes which can contaminate the spectrum or cause voxel mislocalization.
The MR SCIENCE lab has published the first in vivo quantification of transverse relaxation rate T2 for edited glutathione at 7 Tesla. Performed in the human occipital cortex, their method used can be generally applied to calculate the T2 of any measurable metabolite, at great benefit to the investigation of those that exhibit J-evolution from strong coupling. Second-year Biomedical Engineering Ph.D. student Ms. Kelley Swanberg has first-authored the publication, which is currently in press at the Journal of Magnetic Resonance:
Postdoctoral fellow Dr. Karl Landheer and second-year Biomedical Engineering Ph.D. student Ms. Kelley Swanberg receive scholarships to present their work at the GEM-ASEE Doctoral Research Showcase, funded by the National Science Foundation and Alfred P. Sloan Foundation, at the Mayflower Hotel in Washington, D.C. in January 2018.
Postdoctoral fellows Dr. Sebastian Theilenberg and Dr. Karl Landheer and second-year Biomedical Engineering Ph.D. student Ms. Kelley Swanberg receive stipends from the International Society for Magnetic Resonance in Medicine (ISMRM) to present their work at the June 2018 Annual Meeting in Paris, France.
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